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M OLECULAR
O NCOLOGY
EDITED BY
M IGUEL H. B RONCHUD , MD , P h D
M ARY A NN F OOTE , P h D
W ILLIAM P. P ETERS , MD , P h D
M URRAY O. R OBINSON , P h D
HUMANA PRESS
P RINCIPLES OF
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Principles of Molecular Oncology
Principles of
Molecular Oncology
Edited by
Miguel H. Bronchud, MD , P h D
Hospital General of Granollers, Barcelona, Spain
MaryAnn Foote, P h D
Amgen Inc., Thousand Oaks, CA
William P. Peters, P h D
Barbara Ann Karmonos Cancer Institute, The Detroit Medical Center
Wayne State University, Detroit, MI
Murray O. Robinson, MD , P h D
Amgen Inc., Thousand Oaks, CA
Forewords by
E. Donnall Thomas
and
David J. Weatherall
Humana Press
Totowa, New Jersey
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© 2000 Humana Press Inc.
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Printed in the United States of America. 10 9 8 7 6 5 4 3 2 1
Library of Congress Cataloging-in-Publication Data
Principles of molecular oncology / edited by Migual H. Bronchud ... [et al.].
p. cm.
Includes bibliographical references and index.
ISBN 0-89603-581-6 (alk. paper)
1. Carcinogenesis. 2. Cancer—Molecular aspects. I. Bronchud, Miguel H.
[DNLM: 1. Medical Oncology. 2. Molecular Biology. 3. Neoplasms—genetics. QZ 200 P9575 2000]
RC268.5.P75 2000
616.99'2—dc21
DNLM/DLC
99-16733
for Library of Congress
CIP
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