HorseCoatColoursPresentation2008.pdf
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Horse Coat
Colours
Colours
and
and
Horse Coat
Markings
Cindy Harper
Onderstepoort
Laboratory for Applied
Laboratory for Applied
Veterinary Genetics
Onderstepoort
Veterinary Genetics
Basic
Colours
Colours
Basic
Black
Chestnut
Bay
Genetic Control of the Basic
Colours
Colours
Genetic Control of the Basic
produce melanin pigment
2 Pigments responsible for coat and skin
Melanocytes
produce melanin pigment
Melanocytes
2 Pigments responsible for coat and skin
colour
colour –
eumelanin
eumelanin
(black and brown) and
(black and brown) and
phaeomelanin
(red and yellow)
(red and yellow)
phaeomelanin
Colour
genes control either the pigment
genes control either the pigment
producing cell or pigment production
Colour
producing cell or pigment production
2 genes control the main
2 genes control the main
colour
colour
switches
switches
in horses
Extension (E) and Agouti (A)
in horses
Extension (E) and Agouti (A)
Genetics
Locus (address of a gene and each has a
name) occurs on a pair of chromosomes – 1
from sire and 1 from dam
Sire
Dam
Form of gene (allele) on 1 chromosome of pair
can be same as on other – homozygosity
Or different – heterozygosity
Different – dominant and recessive where 1
allele is expressed and other is not
Function: Gene that codes for protein
Protein: Effect e.g. stimulates melanocyte to
produce eumelanin
Chromosome pair
Result: Black horse
The Extension Gene/Locus (E)
Difference between black and red lies in the action of 1
gene
Difference between black and red lies in the action of 1
MC1R
Allele symbols are E and e
gene –
MC1R
Allele symbols are E and e
E extends black (
E extends black (
eumelanin
eumelanin
) in coat
) in coat
e extends red (
phaeomelanin
) in coat
Combination of alleles at the extension locus:
phaeomelanin
) in coat
e extends red (
Combination of alleles at the extension locus:
EE
Allows black in the coat: Black, brown, bay,
buckskin,
Allows black in the coat: Black, brown, bay,
buckskin,
grullo
grullo
Ee
Black in the skin but not in the coat: Chestnut,
palomino
Black in the skin but not in the coat: Chestnut,
ee
palomino
Plik z chomika:
GentykaUmaszczeniaKoni
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