Microarray Technology and Its Applications - U.R. Muller & D.V. Nicolau.pdf

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biological and medical physics,
biomedical engineering
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biological and medical physics,
The fields of biological and medical physics and biomedical engineering are broad, multidisciplinary and
dynamic. They lie at the crossroads of frontier research in physics, biology, chemistry, and medicine. The
Biological and Medical Physics, Biomedical Engineering Series is intended to be comprehensive, covering a
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Books in the series emphasize established and emergent areas of science including molecular, membrane,
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automata. Equally important will be coverage of applied aspects of biological and medical physics and
biomedical engineering such as molecular electronic components and devices, biosensors, medicine, imaging,
physical principles of renewable energy production, advanced prostheses, and environmental control and
engineering.
Editor-in-Chief:
Elias Greenbaum, Oak Ridge National Laboratory,
Oak Ridge, Tennessee, USA
Editorial Board:
Masuo Aizawa, Department of Bioengineering,
Tokyo Institute of Technology, Yokohama, Japan
Olaf S. Andersen, Department of Physiology,
Biophysics & Molecular Medicine,
CornellUniversity,NewYork,USA
Robert H. Austin, Department of Physics,
Princeton University, Princeton, New Jersey, USA
James Barber, Department of Biochemistry,
Imperial College of Science, Technology
and Medicine, London, England
Howard C. Berg, Department of Molecular
and Cellular Biology, Harvard University,
Cambridge, Massachusetts, USA
Victor Bloomf ield, Department of Biochemistry,
University of Minnesota, St. Paul, Minnesota, USA
Robert Callender, Department of Biochemistry,
Albert Einstein College of Medicine,
Bronx, New York, USA
Britton Chance, Department of Biochemistry/
Biophysics, University of Pennsylvania,
Philadelphia, Pennsylvania, USA
Steven Chu, Department of Physics,
Stanford University, Stanford, California, USA
Louis J. DeFelice, Department of Pharmacology,
Vanderbilt University, Nashville, Tennessee, USA
Johann Deisenhofer, Howard Hughes Medical
Institute, The University of Texas, Dallas,
Texas, USA
George Feher, Department of Physics,
University of California, San Diego, La Jolla,
California, USA
Hans Frauenfelder, CNLS, MS B258,
Los Alamos National Laboratory, Los Alamos,
New Mexico, USA
Ivar Giaever, Rensselaer Polytechnic Institute,
Troy,NewYork,USA
biomedical engineering
Sol M. Gruner, Department of Physics,
Princeton University, Princeton, New Jersey, USA
Judith Herzfeld, Department of Chemistry,
Brandeis University, Waltham, Massachusetts, USA
Pierre Joliot, Institute de Biologie
Physico-Chimique, Fondation Edmond
de Rothschild, Paris, France
Lajos Keszthelyi, Institute of Biophysics, Hungarian
Academy of Sciences, Szeged, Hungary
Robert S. Knox, Department of Physics
and Astronomy, University of Rochester, Rochester,
New York, USA
Aaron Lewis, Department of Applied Physics,
Hebrew University, Jerusalem, Israel
Stuart M. Lindsay, Department of Physics
and Astronomy, Arizona State University,
Tempe, Arizona, USA
David Mauzerall, Rockefeller University,
New York, New York, USA
Eugenie V. Mielczarek, Department of Physics
and Astronomy, George Mason University, Fairfax,
Virginia, USA
Markolf Niemz, KlinikumMannheim,
Mannheim, Germany
V. Adrian Parsegian, Physical Science Laboratory,
National Institutes of Health, Bethesda,
Maryland, USA
Linda S. Powers, NCDMF: Electrical Engineering,
Utah State University, Logan, Utah, USA
Earl W. Prohofsky, Department of Physics,
Purdue University, West Lafayette, Indiana, USA
Andrew Rubin, Department of Biophysics, Moscow
State University, Moscow, Russia
Michael Seibert, National Renewable Energy
Laboratory, Golden, Colorado, USA
David Thomas, Department of Biochemistry,
University of Minnesota Medical School,
Minneapolis, Minnesota, USA
Samuel J. Williamson, Department of Physics,
New York University, New York, New York, USA
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U.R. M
uller D.V. Nicolau (Eds.)
Microarray Technology
and Its Applications
With 123 Figures
Including 16 Color Plates
123
uller, Ph.D.
V. P. , Ap p l i e d S c i e n c e
Nanosphere, Inc.
4088 Commercial Avenue
Northbrook, IL 60062
USA
e-mail: umuller@nanosphere.us
¨
Prof. Dan V. Nicolau
Swinburne University of Technology
533-545 Burwood Rd.
Hawthorn, Victoria 3122
Australia
e-mail: dnicolau@swin.edu.au
Library of Congress Cataloging in Publication Data: 2004113284
ISSN 1618-7210
ISBN 3-540-22931-0 Springer Berlin Heidelberg New York
This work is subject to copyright. All rights are reserved, whether thewhole or part of thematerial is concerned,
specif ically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction
on microf ilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is
permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version,
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German Copyright Law.
Springer is a part of Springer Science+Business Media
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© Springer-Verlag Berlin Heidelberg 2005
Printed in Germany
The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply,
even in the absence of a specif ic statement, that such names are exempt from the relevant protective laws and
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SPIN 10884448
57/3141/YL - 5 4 3 2 1 0
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