Medical Toxicology Of Natural Substances-Foods, Fungi, Medicinal Herbs, Plants, And Venomous Animals.pdf
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MEDICAL TOXICOLOGY OF NATURAL SUBSTANCES
MEDICAL TOXICOLOGY OF
NATURAL SUBSTANCES
Foods, Fungi, Medicinal Herbs, Plants, and
Venomous Animals
DONALD G. BARCELOUX, MD, FAACT, FACMT, FACEP
CLINICAL PROFESSOR OF MEDICINE, DEPARTMENT OF EMERGENCY MEDICINE
DAVID GEFFEN SCHOOL OF MEDICINE
UNIVERSITY OF CALIFORNIA AT LOS ANGELES
LOS ANGELES, CALIFORNIA
SENIOR PARTNER, CEP AMERICA
EMERYVILLE, CALIFORNIA
STAFF PHYSICIAN, DEPARTMENT OF EMERGENCY MEDICINE
POMONA VALLEY HOSPITAL MEDICINE CENTER
POMONA, CALIFORNIA
A JOHN WILEY & SONS, INC., PUBLICATION
Copyright © 2008 by John Wiley & Sons, Inc. All rights reserved
Published by John Wiley & Sons, Inc., Hoboken, New Jersey
Published simultaneously in Canada
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Library of Congress Cataloging-in-Publication Data:
Barceloux, Donald G.
Medical toxicology of natural substances : foods, fungi, medicinal herbs, plants, and venomous animals / Donald G. Barceloux.
p. ; cm.
Includesindex.
ISBN 978-0-471-72761-3 (cloth)
1. Natural products–Toxicology. I. Title.
[DNLM: 1. Plants,Toxic. 2. Animals,Poisonous. 3. FoodPoisoning. 4. Furgi. 5. MedicinalHerbs. WD500B242m2008]
RA1211.B285 2008
615.9—dc22
2007051402
Printed in the United States of America
10 9 8 7 6 5 4 3 2 1
To my wife, Kimberly, your loving support and encouragement created the environment to write this book, and
your patience allowed me to focus on this book away from what I enjoy most—being with you.
To my son, Colin, your computer expertise has been immensely helpful solving the technical issues in this book,
and I admire the application of those skills to the development of your own company, Bookrenter.com.
To my daughter, Shannon, sharing your knowledge for the treatment of animals and your passion for becoming
a veterinarian is a great joy for me.
CONTENTS
FOREWORD
xv
PREFACE
xvii
ACKNOWLEDGMENTS
xix
REVIEW PANEL
xxi
PART 1 FOODBORNE and MICROBIAL TOXINS
1
I
Chemical Contamination and Additives
5
by Cyrus Rangan, MD, FAAP
1 FoodContamination
5
2 FoodAdditivesandSensitivities
22
II Staples and Spices
34
3 Akee Fruit and Jamaican Vomiting Sickness
(
Blighia sapida
Köenig)
34
4 Cinnamon(
Cinnamomum
Species)
39
5 Cyanogenic Foods (Cassava, Fruit Kernels, and Cycad Seeds)
44
6 Cycad Seeds and Chronic Neurologic Disease
(
Cycas
Species)
54
7 DjenkolBean[
Archidendron jiringa
(Jack) I. C. Nielsen]
59
8 Grass Pea and Neurolathyrism (
Lathyrus sativus
L.)
62
9 Nutmeg(
Myristica fragrans
Houtt.)
67
10 Pepper and Capsaicin (
Capsicum
and
Piper
Species)
71
11 Potatoes, Tomatoes, and Solanine Toxicity
(
Solanum tuberosum
L.,
Solanum lycopersicum
L.)
77
12 Rhubarb and Oxalosis (
Rheum
Species)
84
vii
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