Stem Cell Biology and Gene Therapy - Peter J. Quesenberry.pdf - medyczne (angielski) - wojtek3101993

Stem Cell Biology and Gene Therapy

Edited by Peter J. Quesenberry, Gary S. Stein, Bernard G. Forget, Sherman M. Weissman

ISBNs: 0-471-14656-0 (Paper); 0-471-22395-6 (Electronic)

STEM CELL BIOLOGY

AND GENE THERAPY

STEMCELLBIOLOGY

ANDGENETHERAPY

Edited by

PETER J. QUESENBERRY

GARY S. STEIN

University of Massachusetts

Worcester, Massachusetts

BERNARD G. FORGET

SHERMAN M. WEISSMAN

Yale University School of Medicine

New Haven, Connecticut

A JOHN WILEY & SONS, INC., PUBLICATION

New York l Chichester l Weinheim l Brisbane l Singapore l Toronto

Designations used by companies to distinguish their products are often

claimed as trademarks. In all instances where John Wiley & Sons, Inc., is

aware of a claim, the product names appear in initial capital or ALL

CAPITAL LETTERS. Readers, however, should contact the appropriate

companies for more complete information regarding trademarks and

registration.

No part of this publication may be reproduced, stored in a retrieval system

or transmitted in any form or by any means, electronic or mechanical,

including uploading, downloading, printing, decompiling, recording or

otherwise, except as permitted under Sections 107 or 108 of the 1976

United States Copyright Act, without the prior written permission of the

Publisher. Requests to the Publisher for permission should be addressed to

the Permissions Department, John Wiley & Sons, Inc., 605 Third Avenue,

New York, NY 10158-0012, (212) 850-6011, fax (212) 850-6008,

E-Mail: PERMREQ@WILEY.COM.

This publication is designed to provide accurate and authoritative

information in regard to the subject matter covered. It is sold with the

understanding that the publisher is not engaged in rendering professional

services. If professional advice or other expert assistance is required, the

services of a competent professional person should be sought.

ISBN 0-471-22395-6

This title is also available in print as ISBN 0-471-14656-0.

For more information about Wiley products, visit our web site at

www.Wiley.com.

CONTENTS

Preface

vii

Contributors

Stem Cell Systems: Basic Principles and Methodologies

Susan K. Nilsson and Peter J. Quesenberry

Cytokine/Growth Factor Responsivenessof Early Hemopoietic

Progenitor Cells

Antony W. Burgess

Molecular Mechanisms Controlling the Cell Cycle and

Proliferation-Differentiation Interrelationships

Gary S. Stein, Andre J. Van Wijnen, Dennet R. Hushka,

Baruch Frenkel, Jane B. Lian, and Janet L. Stein

Stem Cell Transcription

Sherman M. Weissman and Archibald S. Perkins

Hematopoietic Stem Cells: Proliferation, Purification and

Clinical Applications

Ruth Pettengell

133

and Malcolm

A. S. Moore

Delivery Systems for Gene Therapy: The Adenovirus

Thomas Shenk

161

Gene Transfer to Muscle and Spinal Cord Using Herpes

Simplex Virus-Based Vectors

Johnny

179

Huard,

William F. Goins, Giridhar

R. Akkaraju,

David Krisky,

Tom Oligino,

Peggy Marconi,

Charles S. Day, andJoseph

C. Glorioso

CONTENTS

Herpes Virus Vectors

201

Xandra 0. Breakefield, Peter Pechan, Karen Johnston,

and David Jacoby

Delivery Systems for Gene Therapy: Adeno-Associated Virus

Gabriele Kroner- Lux, Christopher E. Walsh,

and Richard Jude Sam&ski

235

Delivery Systems for Gene Therapy: Adeno-Associated

Virus 2

A run Srivastava

257

Ribozyme Gene Therapy Targeting Stem Cells for

Human Immunodeficiency Virus Infection

Anthony D. Ho, Ping Law, Xinqiang Li, and Flossie Wong-Staal

289

Elements of DNA Vaccine Design

Michael J. Caufield and Margaret A. Liu

309

Development of Gene Therapy for Gaucher Disease

J.A. Barranger, E. 0. Rice, J. Dun&an, M. Eljanne, N. Takivama,

M. Nimgaonkar, J. Mierski, M. Beeler, A. Kemp, J. Lancia,dS. Lucot,

S. Schierer-Fochler, J. Mannion-Henderson,

331

T. Mohney, W. Swaney,

A. Bahnson, V. Bansal, and E. Ball

Clinical Applications of Gene Therapy: Correction of Genetic

Disease Affecting Hematopoietic Cells

Jeffrev A. Medin, Johan Richter, and Stefan Karlsson

363

Gene Therapy for Hemophilia

Katherine A. High

385

Clinical Applications of Gene Therapy: Anemias

George F. Atweh and Bernard G. Forget

411

Clinical Applications of Gene Therapy in Cancer: Modification

of Sensitivity to Therapeutic Agents

Thomas Licht, Michael M. Gottesman, and Ira Pastan

429

Clinical Applications of Gene Therapy: Brian Tumors

Kenneth W. Culver and John C. Van Gilder

455

Clinical Applications of Gene Therapy: Cardiovascular Disease

Jonathan C. Fox

471

Applications of Gene Therapy to Neurological Diseases

and Injuries

Derek L. Choi-Lundberg

503

and Martha C. Bohn

Index

555

Stem Cell Biology and Gene Therapy - Peter J. Quesenberry.pdf

Plik z chomika:

Inne pliki z tego folderu:

Inne foldery tego chomika: